Santa Isabel do Rio Negro Vacations

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to $1,045 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Discover the most popular places to visit in Santa Isabel do Rio Negro

Pico da Neblina

Commune with nature and explore the great outdoors at Pico da Neblina during your travels in Santa Isabel do Rio Negro. Discover the mountain views while you're in the area.

Pico da Neblina

Santa Isabel do Rio Negro Hotel Deals

ibis budget Manaus

ibis budget Manaus

3 out of 5
Avenida Djalma Batista 1151 Manaus Amazonas
Fully refundableReserve now, pay when you stay
$41 nightly
The price is $42 total per night from Dec 26 to Dec 27
$42 total
Dec 26 - Dec 27
Total with taxes and fees
8.6/10 Excellent! (1,002 reviews)
Room clean. Breakfast good.staff very nice

Reviewed on Nov 29, 2025

ibis budget Manaus
Hotel Express Vieiralves

Hotel Express Vieiralves

3 out of 5
Rua Rio Branco, s/n Manaus AM
Fully refundableReserve now, pay when you stay
8/10 Very Good! (894 reviews)
Easy chek in and out.

Reviewed on Nov 24, 2025

Get rates
Hotel Express Vieiralves
Rede Andrade Amazônia

Rede Andrade Amazônia

3 out of 5
Av. Getúlio Vargas 227 Manaus AM
Fully refundableReserve now, pay when you stay
$30 nightly
The price is $31 total per night from Dec 9 to Dec 10
$31 total
Dec 9 - Dec 10
Total with taxes and fees
7.8/10 Good! (864 reviews)
Friendly staff specially at the restaurant during breakfast

Reviewed on Oct 9, 2025

Rede Andrade Amazônia
See all 241 properties in Amazonas
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Santa Isabel do Rio Negro Vacation Packages

Santa Isabel do Rio Negro Essential Information

Language
Portuguese
Currency
Brazilian reals
Local Welcome
Olá
Local Goodbye
Adeus

More vacations you might like

All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Frequently asked questions

How much does a Santa Isabel do Rio Negro vacation package cost?
Offering great value package deals on Expedia, you'll be thrilled with how little a vacation to Santa Isabel do Rio Negro costs! Expedia's packages make travel planning easier and save you more.
What are the cheapest months to go to Santa Isabel do Rio Negro?
You can typically find lower rates and greater availability in February, March and April. Take a look at our cheap Santa Isabel do Rio Negro vacation packages and you could get some excellent off-season deals.
How many days is enough for Santa Isabel do Rio Negro?
With a well-planned schedule, you can easily hit the most popular Santa Isabel do Rio Negro attractions in a handful of days. But if you'd like to venture off the beaten track or take day trips, think about booking your Santa Isabel do Rio Negro vacation for longer.
How to find the best Santa Isabel do Rio Negro package deals?
Use Expedia's handy filters to find some unbeatable Santa Isabel do Rio Negro package deals. When you start your search, just set your maximum budget and then order the results by "Price: low to high." If you want to save, plan your break for midweek, or look for Santa Isabel do Rio Negro package deals in the low season. Play around with your travel dates and you may land even bigger discounts. As a rule of thumb, it's typically best to lock in your vacation package well in advance.
Is it cheaper to book a Santa Isabel do Rio Negro vacation as a package?
Expedia vacation packages are designed to give you more bang for your buck. Bundle your hotel, flight and car rental into one great-value price and you could save hundreds of dollars. You'll generally get a better deal than booking each component individually. And you'll still enjoy the flexibility to create a customized Santa Isabel do Rio Negro vacation by choosing your preferred airline, accommodation type and car class.
When to book a vacation package to Santa Isabel do Rio Negro?
If you've got your Santa Isabel do Rio Negro travel dates confirmed, book as soon as you can to snap up some awesome deals. With Expedia, you can generally reserve some flights up to one year ahead of time. Prefer spontaneous trips? Our last-minute deals are perfect for quick escapes.
Does Expedia offer Book Now, Pay Later Santa Isabel do Rio Negro vacation packages?
Secure your dream getaway to Santa Isabel do Rio Negro with Expedia's Book Now, Pay Later vacations. There's no need to scrimp and save or wait for your next payday — we've partnered with online lender Affirm to give you flexibility and choice. Our vacation packages with payment plans let you spread the cost across 3, 6 or 12 months. With no late payment fees or hidden charges, it's easy to budget for your trip and snag great deals while they last.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.